Gefragt von: David Bily
Fragesteller Allgemeines

Tcga Fusion Gene Data Portal

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Zuletzt aktualisiert: 2021-04-06

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Added by: Storm Deetlefs-tait

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Tumor Fusion Gene Data Portal

Based on integrated analysis of paired-end RNA sequencing and DNA copy number data from The Cancer Genome Atlas(TCGA), The Tumor Fusion Gene Data Portal provides a bona-fide fusion list across many tumor types. Figure 1. Fusion transcripts. Fusion transcripts are chimeric mRNAs encoded from the joined parts of two genes, and may occur as a result of genomic rearrangements. Figure 2. …
Url: https://tumorfusions.org/
Tumor Fusion Gene Data Portal

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Welcome to the Pan-Cancer Atlas - Cell

Gao et al. analyze a 9,624 sample TCGA cohort with 33 cancer types to detect gene fusion events. They provide a landscape of fusion events detected, relate fusions to gene expression, focus on kinase fusion structures, examine mutually exclusive mutation and fusion patterns, and highlight fusion druggability. Immunity; The Immune Landscape of Cancer; Thorsson et al. present immunogenomics ...
Url: https://www.cell.com/pb-assets/consortium/PanCancerAtlas/PanCani3/index.html
Welcome to the Pan-Cancer Atlas - Cell

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Added by: Sri Pathmanathan

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Integrative Proteomic Characterization of …

09.07.2020 · To create patient-specific database containing novel alternative splice variants (derived from RNA-Seq data) and fusion proteins (derived from RNA-Seq data), pyQUILTS (Ruggles et al., 2016), an open-source proteogenomic tool, was used to translate novel transcripts in silico into junction-specific peptides using human UniProt proteome database (version 2019-03-07, 20,404 sequences) and …
Url: https://www.sciencedirect.com/science/article/pii/S0092867420306760
Integrative Proteomic Characterization of …

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Proteogenomic insights into the biology and …

08.03.2021 · Raw proteomics data files are hosted by the CPTAC Data Portal and can be accessed at: https: ... Gene fusion detection. Fusions in RNA-seq samples were called using three callers: STAR-Fusion v1.5.0 (Haas et al., 2019), EricScript v0.5.5 (Benelli et al., 2012), and INTEGRATE v0.2.6 (Zhang et al., 2016). As STAR-Fusion has higher sensitivity, calls made by this tool with higher supporting ...
Url: https://www.sciencedirect.com/science/article/pii/S1535610820306553
Proteogenomic insights into the biology and …

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7157 - Gene ResultTP53 tumor protein p53 [ …

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers ...
Url: https://www.ncbi.nlm.nih.gov/gene/7157
7157 - Gene ResultTP53 tumor protein p53 [ …

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Galectin-9 interacts with PD-1 and TIM-3 to …

05.02.2021 · Galectin-9 regulates several cellular processes including TIM-3-mediated T cell death. Here the authors show that co-expressed PD-1 protects TIM-3+ T …
Url: https://www.nature.com/articles/s41467-021-21099-2
Galectin-9 interacts with PD-1 and TIM-3 to …

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Accessing TCGA data from GDC portal

Accessing TCGA data from GDC portal

Added by: Broad Institute

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GTEx Portal: Viewing Gene Expression Data on the GTEx Portal

GTEx Portal: Viewing Gene Expression Data on the GTEx Portal

Added by: National Cancer Institute

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The GDC Data Portal - Video Guides to the Genomic Data Commons

The GDC Data Portal - Video Guides to the Genomic Data Commons

Added by: Bioinformatics Coach

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Download data from TCGA database - A tutorial video

Download data from TCGA database - A tutorial video

Added by: National Human Genome Research Institute

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TCGA: Pathway and Network Analysis of Somatic Mutations Across Cancer Types in TCGA - Ben Raphael

TCGA: Pathway and Network Analysis of Somatic Mutations Across Cancer Types in TCGA - Ben Raphael

Added by: National Human Genome Research Institute

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TCGA: Identification of Gene Fusions Using RNA Sequencing Data - Siyuan Zheng

TCGA: Identification of Gene Fusions Using RNA Sequencing Data - Siyuan Zheng

Added by: Bioinformatics DotCa

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Gene Fusion and Rearrangments

Gene Fusion and Rearrangments

Added by: Bioinformatics DotCa

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Gene Fusion and Rearrangements by Brian Haas

Gene Fusion and Rearrangements by Brian Haas

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Gene Fusion Discovery

Gene Fusion Discovery

Added by: National Human Genome Research Institute

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Using TCGA Data to Inform on Precision Medicine in Late Stage Cancer Settings - Andrew Mungall

Using TCGA Data to Inform on Precision Medicine in Late Stage Cancer Settings - Andrew Mungall
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