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Tcga Portal Mskcc

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Zuletzt aktualisiert: 2021-04-06

Added by: Allison Mccormick

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cBioPortal for Cancer Genomics

Quick select: TCGA PanCancer Atlas Studies Curated set of non-redundant studies. PanCancer Studies Select All; MSK-IMPACT Clinical Sequencing Cohort (MSKCC, Nat Med 2017) 10945 samples. Metastatic Solid Cancers (UMich, Nature 2017) 500 samples. MSS Mixed Solid Tumors (Broad/Dana-Farber, Nat Genet 2018) 249 samples. SUMMIT - Neratinib Basket Study (Multi-Institute, Nature …
Url: http://www.cbioportal.org/
cBioPortal for Cancer Genomics

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Colorectal Cancer Cells Enter a Diapause-like DTP …

07.01.2021 · We extended our analysis to various cancers of the TCGA and found that, for the indicated cancer cohorts, a high autophagy signature corresponds to poor overall survival (p 0.05; hazard ratio [HR]; Figure 7D). These data suggest that patients with a high diapause or autophagy score have tumor cells that would be refractory to therapy. We propose that this signature provides a way to identify ...
Url: https://www.sciencedirect.com/science/article/pii/S009286742031535X
Colorectal Cancer Cells Enter a Diapause-like DTP …

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Added by: Diana Moor

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MutationMapper - cBioPortal for Cancer Genomics

TCGA-B5-A11E: Mutation_Type: Translational effect of variant allele: Missense_Mutation, Nonsense_Mutation, etc. Chromosome: Chromosome number: X, Y, M, 1, 2, etc. Start_Position: Lowest numeric position of the reported variant on the genomic reference sequence: 666: End_Position: Highest numeric position of the reported variant on the genomic reference sequence: 667: Reference_Allele: …
Url: https://www.cbioportal.org/mutation_mapper
MutationMapper - cBioPortal for Cancer Genomics

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Added by: Shi Wen Wu

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cBioportal中文教程 - 简书

对于每对查询的gene(G1和G2),portal计算一个odds ratio(比值比),这个比值比揭示这两个genes在选择的cases中是相互排斥还是共发生。公式如下: 0.jpg. A代表两个genes都发生改变的cases数目. B代表G1改变G2没变的cases数目. C代表G2改变G1没变的cases数目. D代表两者都没发生改变的cases数目. 然后把每一对genes ...
Url: https://www.jianshu.com/p/9ba58976e726
cBioportal中文教程 - 简书

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Network models of primary melanoma …

22.02.2021 · Melanoma is the most lethal skin malignancy, driven by genetic and epigenetic alterations in the complex tumour microenvironment. While large-scale …
Url: https://www.nature.com/articles/s41467-021-21457-0
Network models of primary melanoma …

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Tumor and immune reprogramming during …

Bi et al. dissect the cancer cell and immune microenvironmental transcriptional programs in immune checkpoint blockade-exposed metastatic renal cell carcinoma, revealing immune subpopulation reprogramming and interactions with distinct cancer cell populations in the context of clinical resistance.
Url: https://www.cell.com/cancer-cell/fulltext/S1535-6108(21)00117-3
Tumor and immune reprogramming during …

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Single-cell analysis reveals transcriptomic …

08.01.2021 · Chen et al. perform single-cell analysis and identify transcriptomic remodelling in epithelial cells, macrophages, T cells, fibroblasts and endothelial cells, which together regulate prostate ...
Url: https://www.nature.com/articles/s41556-020-00613-6
Single-cell analysis reveals transcriptomic …

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Colorectal Cancer Cells Enter a Diapause-like DTP …

(B and C) Overall Kaplan-Meier plot for TCGA data for individuals with CRC, stratified to high and low groups based on (B) the embryonic pausing signature (p = 0.02, log rank test) or (C) GO autophagy signature (GO: 0010506; p = 6 × 10 −4, log rank test).
Url: https://www.cell.com/cell/fulltext/S0092-8674(20)31535-X
Colorectal Cancer Cells Enter a Diapause-like DTP …

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TCGA Part I

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Download data from TCGA database - A tutorial video

Added by: National Human Genome Research Institute

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TCGA: Pathway and Network Analysis of Somatic Mutations Across Cancer Types in TCGA - Ben Raphael

Added by: National Human Genome Research Institute

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TCGA: Integrated Genomic Characterization of Endometrial Carcinoma - Douglas Levine

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cBio Cancer Genomics Portal: A Platform for Exploring Cancer Genomics Data: Dr. Ethan Cerami

Added by: National Human Genome Research Institute

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TCGA: Genomic Characterization of Cancer-Adjacent Tissue - Melissa Troester

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Identifying Driver Alterations and Therapeutic Options in Cancer

Added by: National Human Genome Research Institute

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TCGA: Individual Patient Cancer Profiles in The Cancer Genome Atlas - Jianjiong Gao

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Cancer Genomic Databases

Added by: cBioPortal

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The cBioPortal and OncoKB: Making complex cancer genomics data accessible and interpretable