Gefragt von: Crystie Ballard
Fragesteller Allgemeines

Portal Protein Viruses

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Zuletzt aktualisiert: 2022-02-04

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Portal Protein: The Orchestrator of Capsid Assembly for ...

The portal complex is an essential player in all aspects of bacteriophage and herpesvirus assembly. Despite having low sequence similarity, portal structures across bacteriophages share the portal fold and maintain a conserved function. Due to their dynamic role, portal proteins are surprisingly plastic, and their conformations change for each stage of assembly. Because the …
Url: https://pubmed.ncbi.nlm.nih.gov/31337287/
Portal Protein: The Orchestrator of Capsid Assembly for ...

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Thermostable virus portal proteins as reprogrammable ...

07.11.2018 · In double-stranded DNA viruses, the portal protein is incorporated into the capsid shell (Fig. 1a), thereby serving as a natural pore through which DNA is moved in and out 37.
Url: https://www.nature.com/articles/s41467-018-07116-x
Thermostable virus portal proteins as reprogrammable ...

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Human herpesvirus portal proteins: Structure, function ...

Human herpesvirus portal proteins: Structure, function, and antiviral prospects. Herpesviruses (Herpesvirales) and tailed bacteriophages (Caudovirales) package their dsDNA genomes through an evolutionarily conserved mechanism. Much is known about the biochemistry and structural biology of phage portal proteins and the DNA encapsidation (viral ...
Url: https://pubmed.ncbi.nlm.nih.gov/29573302/
Human herpesvirus portal proteins: Structure, function ...

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The Varicella-Zoster Virus Portal Protein Is ... - PubMed

The varicella-zoster virus (VZV) open reading frame 54 (ORF54) gene encodes an 87-kDa monomer that oligomerizes to form the VZV portal protein, pORF54. pORF54 was hypothesized to perform a function similar to that of a previously described herpes simplex virus 1 (HSV-1) homolog, pUL6. pUL6 and the associated viral terminase are required for processing of …
Url: https://pubmed.ncbi.nlm.nih.gov/24807720/
The Varicella-Zoster Virus Portal Protein Is ... - PubMed

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Phage assembly and the special role of the portal protein

Virus infections are ultimately dependent on a successful viral genome delivery to the host cell. The bacteriophage family Caudovirales evolved specialized machinery that fulfills this function: the portal proteins complex. The complexes are arranged as dodecameric rings and are a structural part of capsids incorporated at a five-fold vertex. They are involved in crucial aspects …
Url: https://pubmed.ncbi.nlm.nih.gov/30274853/
Phage assembly and the special role of the portal protein

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Atomic structure of the Epstein-Barr virus portal | Nature ...

29.08.2019 · All herpesviruses contain a linear double-stranded DNA genome, enclosed within an icosahedral capsid. Viral portal protein plays a key role in the procapsid assembly and DNA packaging. The portal...
Url: https://www.nature.com/articles/s41467-019-11706-8
Atomic structure of the Epstein-Barr virus portal | Nature ...

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A Herpes Simplex Virus Scaffold Peptide That Binds the ...

The current studies were undertaken to determine whether the scaffold peptide previously shown to interact with the portal protein could interfere with virus replication when delivered into infected cells. The resulting data provide a novel therapeutic avenue and support for the hypothesis that the portal constitutes the conduit through which DNA uncoats during the …
Url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676109/
A Herpes Simplex Virus Scaffold Peptide That Binds the ...

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Learn Colors Hello Kitty Dough with Ocean Tools and Cookie Molds Surprise Toys Kinder Eggs

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Vlad and story about Worms from the game

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Life Cycle Of Influenza A Animation

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ការលូតលាស់ក្នុងព្រះគុណ

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Stephen Harrison (Harvard) Part 3: Non-enveloped virus entry

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Virus Protein

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How Viruses Work - Molecular Biology Simplified (DNA, RNA, Protein Synthesis)

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T4 Phage Replication

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Searching for a virus-blocking protein

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Replication of DNA viruses