Gefragt von: Mr. Aditya Caprihan
Fragesteller Allgemeines

Sars Cov 2 Portal Of Entry

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Zuletzt aktualisiert: 2022-01-29

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Added by: Stephen Meyers

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Age-dependent appearance of SARS-CoV-2 entry sites in ...

2021-7-15 · SARS-CoV-2 entry genes are differentially expressed in the mouse sensory systems. Focusing on the mouse, where chemosensing takes place in different sensory systems (Fig. 1a), we took advantage of ...
Url: https://www.nature.com/articles/s42003-021-02410-9
Age-dependent appearance of SARS-CoV-2 entry sites in ...

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Added by: Anthony Nelder

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SARS-CoV-2 Entry: At the Crossroads of CD147 and ACE2

In late 2019, the betacoronavirus SARS-CoV-2 was identified as the viral agent responsible for the coronavirus disease 2019 (COVID-19) pandemic. Coronaviruses Spike proteins are responsible for their ability to interact with host membrane receptors and different proteins have been identified as …
Url: https://pubmed.ncbi.nlm.nih.gov/34201214/
SARS-CoV-2 Entry: At the Crossroads of CD147 and ACE2

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Added by: Wai Mi

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SARS-CoV-2 entry factors are highly expressed in nasal ...

2020-4-23 · Similarly to SARS-CoV 5,6, SARS-CoV-2 employs ACE2 as a receptor for cellular entry. The binding affinity of the S protein and ACE2 was found to be a major determinant of SARS-CoV replication rate ...
Url: https://www.nature.com/articles/s41591-020-0868-6
SARS-CoV-2 entry factors are highly expressed in nasal ...

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Added by: Eric Peters

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Identification of two pathways for SARS-CoV-2 entry into …

2021-6-24 · SARS-CoV-2 is the virus that has caused the COVID-19 pandemic. Ideally, to prevent its spread, treatments should target the early stages of infection before the virus penetrates cells. A …
Url: https://phys.org/news/2021-06-identification-pathways-sars-cov-entry-cells.html
Identification of two pathways for SARS-CoV-2 entry into …

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Added by: Bradley Martin

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SARS-CoV-2 Point of Entry Into Cells Captured by Cryo-EM

2020-3-6 · A team of scientists report the cryo-EM structure of the full-length human ACE2 protein—the point of entry for the SARS-CoV-2 virus into human cells.
Url: https://www.genengnews.com/news/sars-cov-2-point-of-entry-into-cells-captured-by-cryo-em/
SARS-CoV-2 Point of Entry Into Cells Captured by Cryo-EM

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Added by: Rose Rusevska

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Cell entry mechanisms of SARS-CoV-2 - PubMed

Third, unlike SARS-CoV, cell entry of SARS-CoV-2 is preactivated by proprotein convertase furin, reducing its dependence on target cell proteases for entry. The high hACE2 binding affinity of the RBD, furin preactivation of the spike, and hidden RBD in the spike potentially allow SARS-CoV-2 to maintain efficient cell entry while evading immune ...
Url: https://pubmed.ncbi.nlm.nih.gov/32376634/
Cell entry mechanisms of SARS-CoV-2 - PubMed

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Added by: Mark Keenan

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Cell entry mechanisms of SARS-CoV-2 | PNAS

2020-5-26 · A key to curbing SARS-CoV-2 is to understand how it enters cells. SARS-CoV-2 and SARS-CoV both use human ACE2 as entry receptor and human proteases as entry activators. Using biochemical and pseudovirus entry assays and SARS-CoV as a comparison, we have identified key cell entry mechanisms of SARS-CoV-2 that potentially contribute to the immune …
Url: https://www.pnas.org/content/117/21/11727
Cell entry mechanisms of SARS-CoV-2 | PNAS

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Added by: Katie Hall

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Inhibitors of SARS-CoV-2 Entry: Current and Future ...

SARS-CoV-2 cell entry also relies on host cell factors. Therefore, these host cell factors can play an essential role as targets for SARS-CoV-2 inhibition. 119 Chlorpromazine (25Table 5) is an antipsychotic drug developed for the treatment of schizophrenia.
Url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315836/
Inhibitors of SARS-CoV-2 Entry: Current and Future ...

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Inhibitors of SARS-CoV-2 Entry: Current and Future ...

Entry model of SARS-CoV-2 into the host cell. Binding of the S1 domain within the spike (S) protein to the cellular ACE2 receptor triggers conformational changes in the S2 domain that results in internalization and subsequent membrane fusion ((A) endosomal/clathrin-dependent pathway). The endosomal pathway is facilitated by a low pH and the pH ...
Url: https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00502
Inhibitors of SARS-CoV-2 Entry: Current and Future ...

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Added by: European Bioinformatics Institute - EMBL-EBI

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UniProt COVID 19 website

UniProt COVID 19 website

Added by: European Bioinformatics Institute - EMBL-EBI

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COVID-19 Data Portal

COVID-19 Data Portal

Added by: CanalDivulgación

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SARS-CoV-2 (Covid-19) Infection Process

SARS-CoV-2 (Covid-19) Infection Process

Added by: Nucleus Medical Media

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How COVID-19 Affects the Body

How COVID-19 Affects the Body

Added by: Helmholtz Gemeinschaft

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Corona: What research is being done?

Corona: What research is being done?

Added by: Emma Hitt Nichols, PhD, Nascent Medical

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SARS CoV-2 Mechanism of Cell Entry

SARS CoV-2 Mechanism of Cell Entry

Added by: Penn Medicine

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COVID-19 Symposium: Entry of Coronavirus into Cells | Dr. Paul Bates

COVID-19 Symposium: Entry of Coronavirus into Cells | Dr. Paul Bates

Added by: Le Soleil, le quotidien de Québec

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SARS CoV 2 entry

SARS CoV 2 entry

Added by: Maastricht4Imaging

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Viral Cell Entry of the SARS-CoV-2 virus - NanoBiology Course 2020 - Monday Group

Viral Cell Entry of the SARS-CoV-2 virus - NanoBiology Course 2020 - Monday Group

Added by: Maastricht4Imaging

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Viral Cell Entry of the SARS-CoV-2 virus - NanoBiology Course 2020 - Tuesday Group

Viral Cell Entry of the SARS-CoV-2 virus - NanoBiology Course 2020 - Tuesday Group
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